
Find hotels in Upstate South Carolina, SC from CA $107
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Go beyond your typical stay in Upstate South Carolina
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Check prices for these dates
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Sep 25 - Sep 26Tomorrow
Sep 26 - Sep 27This weekend
Sep 25 - Sep 27Next weekend
Oct 2 - Oct 4Our top choices for Upstate South Carolina hotels




1. Best Western Spartanburg I-26
Best Western Spartanburg I-26Spartanburg
Santhosh
CA $131
CA $145 total
includes taxes & fees
Oct 11 - Oct 12




2. Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
Anthony
CA $150
CA $167 total
includes taxes & fees
Oct 25 - Oct 26




3. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHGSpartanburg
Michael
CA $146
CA $162 total
includes taxes & fees
Oct 25 - Oct 26




4. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan
Fairfield Inn & Suites by Marriott Greenville Spartanburg/DuncanDuncan
Joseph
CA $168
CA $189 total
includes taxes & fees
Sep 27 - Sep 28




5. Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
Travis
CA $157
CA $175 total
includes taxes & fees
Oct 11 - Oct 12




6. Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
Savannah
CA $129
CA $143 total
includes taxes & fees
Oct 18 - Oct 19




7. Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
Simone
CA $119
CA $131 total
includes taxes & fees
Sep 27 - Sep 28




8. Hampton Inn & Suites Greenville/Spartanburg I-85, SC
Hampton Inn & Suites Greenville/Spartanburg I-85, SCDuncan
Kathy
CA $135
CA $150 total
includes taxes & fees
Oct 12 - Oct 13




9. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
Ryan
CA $107
CA $118 total
includes taxes & fees
Oct 18 - Oct 19




10. Comfort Suites Greenville Airport
Comfort Suites Greenville AirportGreenville
Ryan
CA $131
CA $149 total
includes taxes & fees
Oct 18 - Oct 19




11. stayAPT Suites Greenville Greer BMW
stayAPT Suites Greenville Greer BMWGreer
Robert
CA $168
CA $190 total
includes taxes & fees
Sep 28 - Sep 29




12. Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
Teresa
CA $204
CA $222 total
includes taxes & fees
Sep 27 - Sep 28




13. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
Michael
CA $140
CA $155 total
includes taxes & fees
Oct 4 - Oct 5




14. Extended Stay America Premier Suites - Greenville - Spartanburg - I-85
Extended Stay America Premier Suites - Greenville - Spartanburg - I-85Duncan
Denise
CA $113
CA $125 total
includes taxes & fees
Oct 1 - Oct 2




15. Super 8 by Wyndham Greer/Spartanburg Area
Super 8 by Wyndham Greer/Spartanburg AreaGreer
Tom Frank Frith
CA $95
CA $107 total
includes taxes & fees
Oct 1 - Oct 2




16. Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
Darius
CA $137
CA $155 total
includes taxes & fees
Oct 11 - Oct 12




17. Comfort Suites Simpsonville - Greenville
Comfort Suites Simpsonville - GreenvilleSimpsonville
Lesa
CA $136
CA $150 total
includes taxes & fees
Oct 11 - Oct 12




18. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Hampton Inn & Suites Spartanburg-I-26-Westgate MallSpartanburg
CA $169
CA $188 total
includes taxes & fees
Oct 25 - Oct 26




19. Hilton Garden Inn Spartanburg
Hilton Garden Inn SpartanburgSpartanburg
Yuliya
CA $187
CA $207 total
includes taxes & fees
Oct 25 - Oct 26




20. Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
Leslie
CA $136
CA $152 total
includes taxes & fees
Oct 4 - Oct 5
Vacation Rentals in Upstate South Carolina
Aparthotel




stayAPT Suites Greenville-Haywood Mall
stayAPT Suites Greenville-Haywood MallGreenville
"I was there for work and I was close to everything"
Aparthotel




Landing Apartments - Lyman
Landing Apartments - LymanLyman
"Great room that was nice and clean. Smooth check-in."
Cabin




Carolina Camp Cedar
Carolina Camp CedarPickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Cottage




1 Mi to Downtown Greer: Family Home w/ Gazebo!
1 Mi to Downtown Greer: Family Home w/ Gazebo!Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
Cabin




Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
"Me and my family had a great time"
Apartment




Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
"Excellent location for our trip. Very clean, had everything we needed."
Mobile Home




Carolina Landing RV Resort - Caravan Park
Carolina Landing RV Resort - Caravan ParkFair Play
"Very nice stay with friendly staff"
Cottage




Stunning Lakefront Retreat w/ Dock Access!
Stunning Lakefront Retreat w/ Dock Access!Greenwood
Cottage




9 Mi to Devils Fork State Park: Getaway w/ Porch!
9 Mi to Devils Fork State Park: Getaway w/ Porch!Tamassee
"Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!"
Cottage




Waterfront Cabin w/ Private Dock on Lake Hartwell!
Waterfront Cabin w/ Private Dock on Lake Hartwell!Townville
"We booked last minute for Clemson parents weekend. It worked out fine, it is really in the middle of no where. There are no outlets in the bathroom you have to use the kitchen mirror and outlets to get ready. There was a coffee machine but no coffee. It was very clean. The deck needs some work."
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Stay near popular Upstate South Carolina attractions

Clemson University
9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
BMW Performance Center
9.0/10 (90 reviews)
You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.
Haywood Mall
8.8/10 (1,681 reviews)
During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
Learn more about Upstate South Carolina
Venture to sights like Heritage Park and CCNB Amphitheatre as you discover Upstate South Carolina.
See all hotels in Upstate South Carolina
Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Embassy Suites by Hilton Greenville Downtown Riverplace
10/10 Excellent
"Easy check in and check out. Friendly staff and great Breakfast."
Mint House Greenville Downtown by Kasa
10/10 Excellent
"Great place to stay!would stay again!"
Best Western Plus Greenville I-385 Inn & Suites
10/10 Excellent
"Stephanie at the front desk was very nice and helpful. She was very helpful in helping us find a place to eat. The room was very clean and comfortable. We enjoyed our short stay."
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
10/10 Excellent
"This place is very homy and the manager was so sweet. I loved all decoration(lots of life quotes). I wish they are pet friendly as we traveled with our dog, but no complain! our room was on the 3rd floor and the ice machine on the hallway was not working, but we enjoyed stayed. Lots of places to eat around. There are some resraurants you can walk. The bed was confortable and shower was strong enogh. I hope we have another chance to stay here. Again, Thank you very much!"
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"Great spot"
Grand Bohemian Lodge Greenville, Autograph Collection
10/10 Excellent
"Beautiful hotel with all the amenities! Large rooms and bathrooms, great coffee maker and steamer for clothes. Beautiful views outside of restaurant. Will definitely return!"
Hyatt Place Greenville/Haywood
8/10 Good
"The staff was lovely and the rooms were great nice comfortable bed. We had a really nice view from the window on the fifth floor. The only thing was they were doing renovations which I wasn’t expecting. Other than that everything was great."
More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
1024 Woodruff Rd Greenville SC
CA $99
CA $109 total
Oct 12 - Oct 13
includes taxes & fees
8.4/10 Very good! (1,002 reviews)

Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
CA $107
CA $118 total
Oct 18 - Oct 19
includes taxes & fees
9/10 Wonderful! (1,577 reviews)

Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
CA $115
CA $130 total
Oct 18 - Oct 19
includes taxes & fees

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
CA $149
CA $165 total
Oct 18 - Oct 19
includes taxes & fees

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
CA $149
CA $165 total
Oct 4 - Oct 5
includes taxes & fees
8/10 Very good! (1,000 reviews)

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
CA $154
CA $191 total
Sep 27 - Sep 28
includes taxes & fees
Hotels in Upstate South Carolina with star rating

4 Star Hotels
23 properties

3 Star Hotels
193 properties

2 Star Hotels
155 properties
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