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Find hotels in Upstate South Carolina, SC from CA $91
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
The price is CA $75
CA $83 total
includes taxes & fees
May 12 - May 13

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $92
CA $101 total
includes taxes & fees
May 12 - May 13

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,006 reviews)
The price is CA $204
CA $226 total
includes taxes & fees
May 12 - May 13

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is CA $217
CA $355 total
includes taxes & fees
May 12 - May 13

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,006 reviews)
The price is CA $149
CA $185 total
includes taxes & fees
May 13 - May 14

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (698 reviews)
The price is CA $112
CA $132 total
includes taxes & fees
Jun 3 - Jun 4

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is CA $173
CA $192 total
includes taxes & fees
May 31 - Jun 1

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (227 reviews)
The price is CA $177
CA $194 total
includes taxes & fees
May 17 - May 18

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (710 reviews)
The price is CA $114
CA $124 total
includes taxes & fees
May 17 - May 18

Clemson Memorabilia House
Clemson Memorabilia HouseClemson
9.6 out of 10, Exceptional, (10 reviews)
The price is CA $122
CA $325 total
includes taxes & fees
May 17 - May 18

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (454 reviews)
The price is CA $190
CA $207 total
includes taxes & fees
Jun 5 - Jun 6

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,012 reviews)
The price is CA $150
CA $166 total
includes taxes & fees
May 17 - May 18

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (788 reviews)
The price is CA $139
CA $156 total
includes taxes & fees
May 17 - May 18

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (614 reviews)
The price is CA $150
CA $167 total
includes taxes & fees
May 17 - May 18

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.2 out of 10, Very good, (1,007 reviews)
The price is CA $115
CA $128 total
includes taxes & fees
May 25 - May 26

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (548 reviews)
The price is CA $86
CA $101 total
includes taxes & fees
Jun 7 - Jun 8

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.2 out of 10, Very good, (1,012 reviews)
The price is CA $138
CA $154 total
includes taxes & fees
Jun 9 - Jun 10

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (839 reviews)
The price is CA $156
CA $171 total
includes taxes & fees
Jun 8 - Jun 9

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (736 reviews)
The price is CA $156
CA $175 total
includes taxes & fees
May 25 - May 26

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (845 reviews)
The price is CA $217
CA $241 total
includes taxes & fees
May 12 - May 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (72 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Recent Reviews in Upstate South Carolina

Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is CA $82 per night from Jun 7 to Jun 8
CA $82
CA $91 total
Jun 7 - Jun 8
includes taxes & fees
6/10 (600 reviews)
Hotels in Upstate South Carolina with star rating

4 Star Hotels
36 properties
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