Find hotels in Upstate South Carolina, SC from CA $91

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area

Carolina Inn Anderson Clemson Area
2.5 star property
Anderson
The price is CA $75
CA $83 total
includes taxes & fees
May 12 - May 13
Carolina Inn Anderson Clemson Area

Deluxe Inn

Deluxe Inn
2.0 star property
Mauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $92
CA $101 total
includes taxes & fees
May 12 - May 13
Deluxe Inn

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (1,006 reviews)
"Lovely place to stay right on the lake. "
United States
Sara
The price is CA $204
CA $226 total
includes taxes & fees
May 12 - May 13
Clemson University's James F. Martin Inn

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
The price is CA $217
CA $355 total
includes taxes & fees
May 12 - May 13
Carolina Camp Cedar

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,006 reviews)
"This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!"
United States
Valarie Tina
The price is CA $149
CA $185 total
includes taxes & fees
May 13 - May 14
Lakeside Lodge Clemson

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (698 reviews)
"Very pleasant and helpful staff. Comfortable room though fairly small."
United States
William
The price is CA $112
CA $132 total
includes taxes & fees
Jun 3 - Jun 4
Quality Inn Seneca Clemson Area US-123

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel
3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
"Friendly staff, nice facility that is centrally located."
United States
Frederick
The price is CA $173
CA $192 total
includes taxes & fees
May 31 - Jun 1
Inn on the Square, an Ascend Collection Hotel

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (227 reviews)
"Clean property with friendly staff"
United States
Crystal
The price is CA $177
CA $194 total
includes taxes & fees
May 17 - May 18
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (710 reviews)
"Would stay again breakfast was amazing "
United States
Theresa
The price is CA $114
CA $124 total
includes taxes & fees
May 17 - May 18
Hampton Inn Gaffney

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
The price is CA $122
CA $325 total
includes taxes & fees
May 17 - May 18
Clemson Memorabilia House

Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC
2.5 star property
Greer
9.6 out of 10, Exceptional, (454 reviews)
"great service all around."
United States
Alberto
The price is CA $190
CA $207 total
includes taxes & fees
Jun 5 - Jun 6
Hampton Inn Greer Greenville, SC

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1,012 reviews)
"Great location to area amenities and nice attached restaurant and breakfast buffet."
United States
Erin Kay
The price is CA $150
CA $166 total
includes taxes & fees
May 17 - May 18
Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville
2.5 star property
Greer
8.6 out of 10, Excellent, (788 reviews)
"Wonderful stay - everything was perfect "
United States
Paula
The price is CA $139
CA $156 total
includes taxes & fees
May 17 - May 18
Comfort Inn & Suites Greer - Greenville

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.2 out of 10, Wonderful, (614 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is CA $150
CA $167 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very good, (1,007 reviews)
"Front desk staff were very friendly. We had a welcoming and quiet 1 night stay."
United States
Nicole
The price is CA $115
CA $128 total
includes taxes & fees
May 25 - May 26
Microtel Inn & Suites by Wyndham Anderson/Clemson

Quality Inn Clinton - Laurens I-26

Quality Inn Clinton - Laurens I-26
2.5 star property
Clinton
7.4 out of 10, Good, (548 reviews)
"Clean room, easy parking, we were plenty comfortable."
United States
Christine
The price is CA $86
CA $101 total
includes taxes & fees
Jun 7 - Jun 8
Quality Inn Clinton - Laurens I-26

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very good, (1,012 reviews)
"Great breakfast and friendly staff made our stay enjoyable."
United States
Lon
The price is CA $138
CA $154 total
includes taxes & fees
Jun 9 - Jun 10
Comfort Inn & Suites Clemson - University Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (839 reviews)
"Great location and facilities"
United States
Brian
The price is CA $156
CA $171 total
includes taxes & fees
Jun 8 - Jun 9
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Clinton - I-26

Hampton Inn & Suites Clinton - I-26
2.5 star property
Clinton
9.0 out of 10, Wonderful, (736 reviews)
"Clean room, delicious breakfast, nice pool area"
United States
Priscilla
The price is CA $156
CA $175 total
includes taxes & fees
May 25 - May 26
Hampton Inn & Suites Clinton - I-26

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (845 reviews)
"We always wanted to stay here whenever we were visiting Clemson, and we finally did … and we’re not disappointed. Our stay was great!"
United States
Roberto
The price is CA $217
CA $241 total
includes taxes & fees
May 12 - May 13
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Upstate South Carolina

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Upstate South Carolina attractions

Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

Recent Reviews in Upstate South Carolina

More cheap stays in Upstate South Carolina

Hotels in Upstate South Carolina with star rating

Explore a world of travel with Expedia